Functions of SAM-e in the body
- Helps maintain and improve joint health
- Helps relieve pain and joint swelling
- Improves ease of movement and joint mobility
- Supports positive mood and energy levels
- Helps maintain liver health
SAM-e is generally used for pain, stiffness and joint swelling, it may also improve mobility, help rebuild cartilage and may even reduce symptoms of osteoarthritis (OA) and depression.
SAM-e is also a major component in the synthesis of nucleic acids, proteins, hormones, and phospholipids. In a 2002 U.S. Department of Health and Human Services study demonstrated it to be effective in helping maintain both mood stability and joint function. It also helps maintain acetylcholine levels, that are so important for correct cognitive function.
SAM-e (from 800mg of s-adenosyl-l-methionine tosylate) 400mg.
Other Ingredients: Callulose, silica, magnesium stearate, ethyl cellulose, oleic acid, medium chain triglycerides, sodium alginate, modified cellulose, triacetin, calcium carbonate, and riboflavin (for colour).
No sugar, salt, dairy, wheat, gluten, corn, soy, preservatives, artificial colours or flavours.
As a dietary supplement, adults take one enteric-coated tablet daily (a specific a material which help prevent or minimize dissolution in the stomach but allows dissolution in the small intestine), or as directed by a healthcare professional.
Store in a cool, dry place, away from direct light.
Do not exceed the recommended daily dose. Keep out of reach of young children. Nutritional supplements should not replace a varied and balanced diet and a healthy lifestyle. Children, pregnant women and women who are breastfeeding, should consult their doctor before use. Check with simultaneous intake of medicines. No long-term use without professional advice.
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Schrötter A, Pfeiffer K, El Magraoui F, Platta HW, Erdmann R, Meyer HE, Egensperger R, Marcus K, Müller T. The amyloid precursor protein (APP) family members are key players in S-adenosylmethionine formation by MAT2A and modify BACE1 and PSEN1 gene expression-relevance for Alzheimer’s disease. Mol Cell Proteomics. 2012 Nov;11(11):1274-88.
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Michael Brown J, Ball JG, Wright MS, Van Meter S, Valentovic MA. Novel protective mechanisms for S-adenosyl-L-methionine against acetaminophen hepatotoxicity: improvement of key antioxidant enzymatic function. Toxicol Lett. 2012 Aug 3;212(3):320-8.